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CMap Candidate Details

Structure:
CMap ID: C03650
Pert ID: BRD-A78877355
Compound Name: nefopam
Targets:
MoA: cyclooxygenase inhibitor
SMILES: CN1CCOC(c2ccccc2)c2ccccc2C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4323 BRD-A78877355 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
5012 BRD-A78877355 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.61
37255 BRD-A78877355 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37554 BRD-A78877355 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37855 BRD-A78877355 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38396 BRD-A78877355 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38889 BRD-A78877355 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
100332 BRD-A78877355 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
127371 BRD-A78877355 A375 10 uM 24 h -0.34 -1.41 1.42 0.24 0.86 0.15
127448 BRD-A78877355 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127538 BRD-A78877355 JURKAT 1.11 uM 24 h 0.31 1.3 0.73 0.0 0.0 0.0
127585 BRD-A78877355 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127626 BRD-A78877355 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
127711 BRD-A78877355 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135383 BRD-A78877355 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.46
135419 BRD-A78877355 HT29 0.01 uM 24 h -0.22 -0.9 0.04 -0.39 -1.31 1.71
135452 BRD-A78877355 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
135508 BRD-A78877355 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).