Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03661
Pert ID: BRD-K04112579
Compound Name: nepafenac
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122559 BRD-K04112579 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122614 BRD-K04112579 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122666 BRD-K04112579 HT29 0.04 uM 24 h 0.26 1.06 0.19 0.23 0.83 0.12
122693 BRD-K04112579 MCF10A 0.125 uM 24 h 0.24 1.02 0.13 0.27 0.97 0.35
122782 BRD-K04112579 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122806 BRD-K04112579 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.21 -0.7 0.03
130854 BRD-K04112579 A375 0.74 uM 24 h -0.26 -1.1 0.33 0.27 0.97 0.35
130896 BRD-K04112579 HA1E 0.74 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
130946 BRD-K04112579 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
131014 BRD-K04112579 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131068 BRD-K04112579 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131100 BRD-K04112579 MDAMB231 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).