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CMap Candidate Details

Structure:
CMap ID: C03673
Pert ID: BRD-K83354763
Compound Name: NFKB-activation-inhibitor-II
Targets: RELA
MoA: NFkB pathway inhibitor
SMILES: Cc1ccc(NCCCc2ccccc2)c(N)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8997 BRD-K83354763 A375 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9244 BRD-K83354763 A549 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9526 BRD-K83354763 AGS 6.66 uM 6 h -0.25 -1.05 0.23 -0.21 -0.7 0.03
9831 BRD-K83354763 H1299 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10087 BRD-K83354763 HA1E 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10317 BRD-K83354763 HCC515 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10609 BRD-K83354763 HCT116 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11593 BRD-K83354763 NCIH2073 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11854 BRD-K83354763 NCIH508 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12151 BRD-K83354763 NCIH596 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12884 BRD-K83354763 SW480 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13374 BRD-K83354763 U937 6.66 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13508 BRD-K83354763 VCAP 6.66 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119645 BRD-K83354763 HEPG2 10 uM 24 h 0.26 1.08 0.21 0.0 0.0 0.0
119682 BRD-K83354763 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119719 BRD-K83354763 JURKAT 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
119770 BRD-K83354763 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119805 BRD-K83354763 PC3 10 uM 24 h -0.18 -0.77 0.0 -0.31 -1.04 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).