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CMap Candidate Details

Structure:
CMap ID: C03675
Pert ID: BRD-K05181084
Compound Name: NGB-2904
Targets: DRD3
MoA: dopamine receptor antagonist
SMILES: Clc1cccc(N2CCN(CCCCNC(=O)c3ccc-4c(Cc5ccccc-45)c3)CC2)c1Cl
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1532 BRD-K05181084 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1870 BRD-K05181084 HCC515 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
2208 BRD-K05181084 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2698 BRD-K05181084 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41708 BRD-K05181084 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42045 BRD-K05181084 A549 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
42268 BRD-K05181084 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42604 BRD-K05181084 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42908 BRD-K05181084 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43282 BRD-K05181084 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43463 BRD-K05181084 NPC 10 uM 24 h 0.18 0.74 0.0 -0.28 -0.95 0.41
43770 BRD-K05181084 PHH 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
44049 BRD-K05181084 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
99992 BRD-K05181084 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).