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CMap Candidate Details

Structure:
CMap ID: C03690
Pert ID: BRD-K28912512
Compound Name: nicotinamide
Targets: BST1|LDHA|PARP1|SIRT5
MoA: protein synthesis stimulant
SMILES: NC(=O)c1cccnc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22734 BRD-K28912512 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23021 BRD-K28912512 HEPG2 10 uM 6 h -0.21 -0.86 0.02 -0.29 -0.98 0.48
24296 BRD-K28912512 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.4
91214 BRD-K28912512 HUH7 25 uM 72 h 0.28 1.16 0.36 -0.2 -0.68 0.02
98881 BRD-K28912512 NEU 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.61
99136 BRD-K28912512 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121953 BRD-K28912512 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
122003 BRD-K28912512 HT29 0.125 uM 24 h 0.29 1.21 0.46 -0.23 -0.77 0.08
122039 BRD-K28912512 HUVEC 0.04 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
122104 BRD-K28912512 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130182 BRD-K28912512 A375 0.74 uM 24 h 0.18 0.75 0.0 0.21 0.74 0.03
130197 BRD-K28912512 A549 0.03 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.52
130220 BRD-K28912512 HA1E 0.25 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
130282 BRD-K28912512 HELA 2.22 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
130341 BRD-K28912512 JURKAT 0.08 uM 24 h 0.28 1.15 0.34 0.0 0.0 0.0
130391 BRD-K28912512 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130446 BRD-K28912512 MDAMB231 0.74 uM 24 h 0.26 1.1 0.24 -0.3 -1.0 0.53
130476 BRD-K28912512 PC3 0.03 uM 24 h -0.22 -0.94 0.07 -0.29 -0.96 0.44
130492 BRD-K28912512 THP1 0.01 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
130517 BRD-K28912512 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).