Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03701
Pert ID: BRD-A00100033
Compound Name: nifurtimox
Targets:
MoA: DNA inhibitor
SMILES: CC1CS(=O)(=O)CCN1N=Cc1ccc(o1)[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4152 BRD-A00100033 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4265 BRD-A00100033 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4732 BRD-A00100033 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4976 BRD-A00100033 VCAP 10 uM 6 h -0.25 -1.04 0.21 0.0 0.0 0.0
37030 BRD-A00100033 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37206 BRD-A00100033 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37420 BRD-A00100033 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37968 BRD-A00100033 HT29 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
38261 BRD-A00100033 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
38274 BRD-A00100033 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
38586 BRD-A00100033 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38804 BRD-A00100033 SKB 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).