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CMap Candidate Details

Structure:
CMap ID: C03702
Pert ID: BRD-K59333713
Compound Name: niguldipine-(S)-(+)
Targets: ADRA1A
MoA: adrenergic receptor antagonist
SMILES: COC(=O)C1=C(C)NC(C)=C([C@H]1c1cccc(c1)[N+]([O-])=O)C(=O)OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
85005 BRD-K59333713 A375 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.92
85097 BRD-K59333713 A549 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
85197 BRD-K59333713 HA1E 10 uM 24 h 0.27 1.13 0.29 -0.32 -1.07 0.78
85307 BRD-K59333713 HCC515 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
85408 BRD-K59333713 HEPG2 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
85509 BRD-K59333713 HT29 10 uM 24 h -0.2 -0.83 0.0 -0.27 -0.92 0.33
85607 BRD-K59333713 MCF??7.00 4 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
85700 BRD-K59333713 PC3 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99704 BRD-K59333713 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).