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CMap Candidate Details

Structure:
CMap ID: C03723
Pert ID: BRD-A02006392
Compound Name: nitrendipine
Targets: CACNA1C|CACNA1D|CACNA1H|CACNA1S|CACNA2D1|CACNA2D2|CACNB2|CACNG1|KCNN4
MoA: calcium channel blocker
SMILES: CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(c1)[N+]([O-])=O)C(=O)OC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5141 BRD-A02006392 A375 10 uM 6 h -0.23 -0.96 0.1 0.29 1.03 0.51
5486 BRD-A02006392 HCC515 10 uM 24 h -0.2 -0.85 0.01 -0.24 -0.81 0.13
6445 BRD-A02006392 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9260 BRD-A02006392 AGS 10 uM 6 h -0.23 -0.97 0.11 -0.28 -0.94 0.37
9563 BRD-A02006392 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10377 BRD-A02006392 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10645 BRD-A02006392 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.71 0.03
11313 BRD-A02006392 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11884 BRD-A02006392 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12639 BRD-A02006392 SW480 10 uM 6 h -0.24 -0.99 0.14 0.21 0.76 0.05
12974 BRD-A02006392 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13122 BRD-A02006392 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44470 BRD-A02006392 A549 10 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
44740 BRD-A02006392 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46173 BRD-A02006392 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46488 BRD-A02006392 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52072 BRD-A02006392 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91036 BRD-A02006392 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
95630 BRD-A02006392 U2OS 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
98728 BRD-A02006392 NPC 10 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
98837 BRD-A02006392 NEU 10 uM 24 h -0.26 -1.1 0.34 -0.28 -0.93 0.34
120908 BRD-A02006392 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120949 BRD-A02006392 HEK293 10 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
121000 BRD-A02006392 HELA 1.11 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
121016 BRD-A02006392 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.27 0.96 0.33
121106 BRD-A02006392 YAPC 1.11 uM 24 h 0.23 0.95 0.06 -0.43 -1.44 15.35
129220 BRD-A02006392 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).