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CMap Candidate Details

Structure:
CMap ID: C03730
Pert ID: BRD-K73589491
Compound Name: nizatidine
Targets: HRH2
MoA: histamine receptor antagonist
SMILES: CN\C(NCCSCc1csc(CN(C)C)n1)=C/[N+]([O-])=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4250 BRD-K73589491 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4480 BRD-K73589491 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4821 BRD-K73589491 PC3 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
24475 BRD-K73589491 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25041 BRD-K73589491 MCF??7.00 10 uM 24 h 0.19 0.8 0.0 -0.3 -1.01 0.58
25533 BRD-K73589491 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37308 BRD-K73589491 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37731 BRD-K73589491 ASC 10 uM 24 h 0.0 0.0 0.0 0.35 1.24 1.24
37942 BRD-K73589491 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38105 BRD-K73589491 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38548 BRD-K73589491 NPC 10 uM 24 h -0.22 -0.93 0.07 0.21 0.74 0.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).