CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03748
Pert ID:	BRD-K12539581
Compound Name:	nocodazole
Targets:	HPGDS
MoA:	tubulin polymerization inhibitor
SMILES:	COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1cccs1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1144	BRD-K12539581	A549	0.12 uM	24 h	0.17	0.69	0.0	-0.37	-1.25	1.35
1176	BRD-K12539581	PC3	10 uM	24 h	-0.23	-0.97	0.11	-0.4	-1.36	2.02
1307	BRD-K12539581	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
1358	BRD-K12539581	U2OS	0.12 uM	48 h	-0.16	-0.67	0.0	0.0	0.0	0.0
5186	BRD-K12539581	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
5431	BRD-K12539581	HA1E	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.85	0.2
5580	BRD-K12539581	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5884	BRD-K12539581	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
6004	BRD-K12539581	HT29	10 uM	6 h	0.0	0.0	0.0	-0.3	-1.01	0.58
6350	BRD-K12539581	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
37596	BRD-K12539581	ASC	10 uM	24 h	0.19	0.78	0.0	0.0	0.0	0.0
38691	BRD-K12539581	PHH	10 uM	24 h	0.21	0.89	0.02	0.18	0.64	0.0
98132	BRD-K12539581	NPC	10 uM	24 h	0.0	0.0	0.0	-0.38	-1.26	1.39
98340	BRD-K12539581	NEU	10 uM	24 h	0.0	0.0	0.0	-0.41	-1.38	2.02

Summary