CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03755
Pert ID:	BRD-K63165456
Compound Name:	norcyclobenzaprine
Targets:
MoA:	adrenergic receptor agonist; serotonin receptor antagonist
SMILES:	CNCCC=C1c2ccccc2C=Cc2ccccc12
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
4231	BRD-K63165456	HA1E	10 uM	6 h	-0.26	-1.09	0.33	0.27	0.94	0.29
4455	BRD-K63165456	HCC515	10 uM	24 h	-0.17	-0.72	0.0	0.0	0.0	0.0
4701	BRD-K63165456	PC3	10 uM	24 h	-0.25	-1.03	0.2	0.0	0.0	0.0
5103	BRD-K63165456	VCAP	10 uM	6 h	0.0	0.0	0.0	-0.37	-1.25	1.35
39155	BRD-K63165456	A375	10 uM	6 h	0.0	0.0	0.0	-0.33	-1.1	0.88
39335	BRD-K63165456	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
39729	BRD-K63165456	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
40026	BRD-K63165456	HEPG2	10 uM	6 h	-0.31	-1.27	0.74	0.0	0.0	0.0
40299	BRD-K63165456	HT29	10 uM	6 h	0.0	0.0	0.0	0.3	1.05	0.57
40626	BRD-K63165456	MCF??7.00	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40840	BRD-K63165456	NEU	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
41147	BRD-K63165456	NPC	10 uM	24 h	0.21	0.88	0.02	-0.3	-1.01	0.57
41485	BRD-K63165456	SKB	10 uM	24 h	0.26	1.09	0.23	0.3	1.05	0.57
99318	BRD-K63165456	U2OS	8 uM	6 h	0.22	0.91	0.03	0.23	0.8	0.08

Summary