Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03758
Pert ID: BRD-K92073408
Compound Name: norethindrone
Targets: PGR
MoA: progesterone receptor agonist
SMILES: C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1659 BRD-K92073408 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
2141 BRD-K92073408 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2230 BRD-K92073408 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2547 BRD-K92073408 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
39224 BRD-K92073408 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39371 BRD-K92073408 A549 10 uM 24 h -0.26 -1.08 0.29 0.0 0.0 0.0
39827 BRD-K92073408 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40116 BRD-K92073408 HEPG2 10 uM 6 h -0.34 -1.4 1.14 0.0 0.0 0.0
40377 BRD-K92073408 HT29 10 uM 6 h 0.0 0.0 0.0 0.26 0.9 0.22
40661 BRD-K92073408 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40925 BRD-K92073408 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41249 BRD-K92073408 NPC 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.33 1.75
91264 BRD-K92073408 HUH7 12 uM 72 h -0.26 -1.07 0.28 -0.29 -0.97 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).