CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03789
Pert ID:	BRD-A80213327
Compound Name:	NSC-23766
Targets:
MoA:	Ras GTPase inhibitor
SMILES:	CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
7119	BRD-A80213327	A549	10 uM	6 h	-0.27	-1.14	0.42	-0.38	-1.29	1.53
9313	BRD-A80213327	AGS	150 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10120	BRD-A80213327	HCC515	150 uM	24 h	0.2	0.85	0.01	0.0	0.0	0.0
10692	BRD-A80213327	HEPG2	150 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11056	BRD-A80213327	HT29	150 uM	6 h	0.0	0.0	0.0	-0.4	-1.35	1.88
11134	BRD-A80213327	MCF??7.00	150 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
11369	BRD-A80213327	NCIH2073	150 uM	6 h	-0.21	-0.89	0.03	0.0	0.0	0.0
11675	BRD-A80213327	NCIH508	150 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11938	BRD-A80213327	NCIH596	150 uM	6 h	0.0	0.0	0.0	-0.46	-1.53	15.35
12225	BRD-A80213327	NOMO1	150 uM	6 h	-0.26	-1.07	0.27	-0.3	-1.01	0.57
12434	BRD-A80213327	PC3	150 uM	24 h	0.0	0.0	0.0	-0.23	-0.76	0.07
12690	BRD-A80213327	SW480	150 uM	6 h	-0.23	-0.98	0.12	-0.3	-1.02	0.6
12936	BRD-A80213327	THP1	150 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13167	BRD-A80213327	U937	150 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
13552	BRD-A80213327	VCAP	150 uM	6 h	0.0	0.0	0.0	-0.38	-1.26	1.38
91065	BRD-A80213327	HUH7	1.11 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
100339	BRD-A80213327	U2OS	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
118059	BRD-A80213327	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
118145	BRD-A80213327	HA1E	10 uM	24 h	0.0	0.0	0.0	-0.27	-0.9	0.28

Summary