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CMap Candidate Details

Structure:
CMap ID: C03807
Pert ID: BRD-K48692744
Compound Name: NU-1025
Targets: PARP1
MoA: PARP inhibitor
SMILES: Cc1nc2c(O)cccc2c(=O)[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8944 BRD-K48692744 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9432 BRD-K48692744 AGS 10 uM 6 h -0.26 -1.07 0.27 0.31 1.11 0.73
10058 BRD-K48692744 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10274 BRD-K48692744 HCC515 10 uM 6 h -0.26 -1.07 0.28 0.0 0.0 0.0
10524 BRD-K48692744 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10791 BRD-K48692744 HEPG2 10 uM 6 h -0.24 -0.98 0.13 0.0 0.0 0.0
10978 BRD-K48692744 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11496 BRD-K48692744 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.58
11772 BRD-K48692744 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12459 BRD-K48692744 PC3 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.06
12968 BRD-K48692744 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13281 BRD-K48692744 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13626 BRD-K48692744 VCAP 10 uM 6 h 0.22 0.93 0.05 0.18 0.62 0.0
44593 BRD-K48692744 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44976 BRD-K48692744 ASC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.38 2.02
46092 BRD-K48692744 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46408 BRD-K48692744 PHH 10 uM 24 h 0.19 0.78 0.0 0.41 1.44 2.21
46730 BRD-K48692744 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90583 BRD-K48692744 MCF??7.00 5e-04 uM 24 h -0.23 -0.96 0.09 0.3 1.07 0.62
99593 BRD-K48692744 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).