CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00381
Pert ID:	BRD-K01493881
Compound Name:	apigenin
Targets:	AKR1B1\|AR\|CDK6\|CFTR\|CYP19A1\|CYP1B1\|HSD17B1
MoA:	casein kinase inhibitor; cell proliferation inhibitor
SMILES:	Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
33662	BRD-K01493881	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
34024	BRD-K01493881	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
34300	BRD-K01493881	HA1E	10 uM	6 h	0.27	1.13	0.29	0.23	0.82	0.1
34539	BRD-K01493881	HCC515	10 uM	6 h	0.0	0.0	0.0	0.22	0.78	0.06
34807	BRD-K01493881	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.28	1.0	0.42
35076	BRD-K01493881	HT29	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
35444	BRD-K01493881	MCF??7.00	10 uM	6 h	0.19	0.78	0.0	-0.19	-0.63	0.0
35529	BRD-K01493881	NEU	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
35922	BRD-K01493881	PC3	10 uM	24 h	0.0	0.0	0.0	0.24	0.84	0.13
36180	BRD-K01493881	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
36474	BRD-K01493881	SKB	10 uM	24 h	0.2	0.85	0.01	0.28	0.99	0.4
36760	BRD-K01493881	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96102	BRD-K01493881	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
99210	BRD-K01493881	NPC	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary