Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03810
Pert ID: BRD-K00337317
Compound Name: NU-7441
Targets: PRKDC
MoA: DNA dependent protein kinase inhibitor
SMILES: O=c1cc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33763 BRD-K00337317 A549 10 uM 24 h -0.2 -0.82 0.0 0.0 0.0 0.0
34021 BRD-K00337317 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34804 BRD-K00337317 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35289 BRD-K00337317 MCF??7.00 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
35527 BRD-K00337317 NEU 10 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
35712 BRD-K00337317 NPC 10 uM 24 h -0.25 -1.02 0.18 0.0 0.0 0.0
36053 BRD-K00337317 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36177 BRD-K00337317 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36471 BRD-K00337317 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36758 BRD-K00337317 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91500 BRD-K00337317 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91981 BRD-K00337317 A375 3.33 uM 24 h 0.29 1.22 0.48 0.0 0.0 0.0
92055 BRD-K00337317 HA1E 10 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
92086 BRD-K00337317 HCC515 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
92125 BRD-K00337317 HS578T 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
92177 BRD-K00337317 HT29 10 uM 24 h 0.25 1.05 0.18 0.0 0.0 0.0
92207 BRD-K00337317 MCF10A 10 uM 24 h -0.2 -0.82 0.0 0.24 0.83 0.12
92282 BRD-K00337317 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.2
92386 BRD-K00337317 SKBR3 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).