Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00383
Pert ID: BRD-K64990520
Compound Name: apocynin
Targets: NOX4
MoA: NADPH oxidase inhibitor
SMILES: COc1cc(ccc1O)C(C)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124284 BRD-K64990520 A375 0.04 uM 24 h 0.25 1.06 0.18 -0.26 -0.88 0.25
124334 BRD-K64990520 HEK293 0.04 uM 24 h 0.24 0.99 0.09 -0.33 -1.1 0.87
124373 BRD-K64990520 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124443 BRD-K64990520 JURKAT 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124458 BRD-K64990520 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124504 BRD-K64990520 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.03
132373 BRD-K64990520 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132404 BRD-K64990520 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
132477 BRD-K64990520 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.34
132542 BRD-K64990520 MCF??7.00 0.03 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
132580 BRD-K64990520 PC3 0.74 uM 24 h 0.2 0.84 0.0 0.32 1.13 0.82
132632 BRD-K64990520 THP1 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132652 BRD-K64990520 YAPC 0.03 uM 24 h 0.23 0.94 0.06 -0.34 -1.16 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).