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CMap Candidate Details

Structure:
CMap ID: C03834
Pert ID: BRD-K82522873
Compound Name: N6022
Targets: ADH5
MoA: alcohol dehydrogenase inhibitor
SMILES: Cc1cc(ccc1-n1c(CCC(O)=O)ccc1-c1ccc(cc1)-n1ccnc1)C(N)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125556 BRD-K82522873 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125623 BRD-K82522873 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125704 BRD-K82522873 HUVEC 10 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
125760 BRD-K82522873 JURKAT 0.125 uM 24 h -0.28 -1.16 0.46 0.0 0.0 0.0
125812 BRD-K82522873 MCF??7.00 10 uM 24 h 0.32 1.32 0.78 0.0 0.0 0.0
125860 BRD-K82522873 PC3 0.125 uM 24 h 0.21 0.86 0.01 0.0 0.0 0.0
125884 BRD-K82522873 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125903 BRD-K82522873 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133654 BRD-K82522873 A549 0.01 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
133719 BRD-K82522873 HEK293 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133748 BRD-K82522873 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
133780 BRD-K82522873 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
133838 BRD-K82522873 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133896 BRD-K82522873 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).