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CMap Candidate Details

Structure:
CMap ID: C03837
Pert ID: BRD-K18316707
Compound Name: O-1918
Targets:
MoA: cannabinoid receptor antagonist
SMILES: COc1cc(C)cc(OC)c1[C@@H]1C=C(C)CC[C@H]1C(C)=C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2845 BRD-K18316707 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3150 BRD-K18316707 HCC515 10 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
3470 BRD-K18316707 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3735 BRD-K18316707 VCAP 10 uM 24 h 0.21 0.88 0.02 -0.28 -0.95 0.4
44329 BRD-K18316707 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44539 BRD-K18316707 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.16
44885 BRD-K18316707 ASC 10 uM 24 h -0.28 -1.17 0.5 0.24 0.83 0.12
45188 BRD-K18316707 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45456 BRD-K18316707 HT29 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.12
45786 BRD-K18316707 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.23 0.82 0.1
46003 BRD-K18316707 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46321 BRD-K18316707 PHH 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.13 0.97
46636 BRD-K18316707 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).