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CMap Candidate Details

Structure:
CMap ID: C03841
Pert ID: BRD-K15600710
Compound Name: obatoclax
Targets: BCL2
MoA: BCL inhibitor
SMILES: COC1=CC(=N\C\1=C/c1[nH]c(C)cc1C)c1cc2ccccc2[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1185 BRD-K15600710 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1222 BRD-K15600710 A549 0.12 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.37
1281 BRD-K15600710 MCF??7.00 0.12 uM 48 h 0.0 0.0 0.0 -0.23 -0.77 0.08
1321 BRD-K15600710 U2OS 1.11 uM 24 h -0.22 -0.92 0.06 0.25 0.88 0.18
29793 BRD-K15600710 A375 10 uM 6 h 0.21 0.87 0.01 0.0 0.0 0.0
30375 BRD-K15600710 ASC 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
30694 BRD-K15600710 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.61
30977 BRD-K15600710 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.42 3.53
31281 BRD-K15600710 HEPG2 10 uM 6 h -0.27 -1.11 0.36 0.0 0.0 0.0
31527 BRD-K15600710 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
32141 BRD-K15600710 NEU 10 uM 24 h -0.27 -1.14 0.43 -0.44 -1.5 15.35
32365 BRD-K15600710 NPC 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
32957 BRD-K15600710 SKB 10 uM 24 h 0.25 1.03 0.13 -0.29 -0.96 0.43
33436 BRD-K15600710 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).