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CMap Candidate Details

Structure:
CMap ID: C03863
Pert ID: BRD-K92303087
Compound Name: oglemilast
Targets:
MoA: phosphodiesterase inhibitor
SMILES: CS(=O)(=O)Nc1ccc2oc3c(OC(F)F)ccc(C(=O)Nc4c(Cl)cncc4Cl)c3c2c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96803 BRD-K92303087 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128099 BRD-K92303087 A375 10 uM 24 h -0.18 -0.75 0.0 -0.3 -1.01 0.56
128160 BRD-K92303087 HEK293 0.37 uM 24 h -0.28 -1.18 0.5 0.0 0.0 0.0
128199 BRD-K92303087 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128251 BRD-K92303087 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128278 BRD-K92303087 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.53
135767 BRD-K92303087 A549 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135789 BRD-K92303087 HA1E 0.74 uM 24 h -0.22 -0.91 0.05 -0.37 -1.23 1.28
135874 BRD-K92303087 HELA 0.74 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
135927 BRD-K92303087 HT29 2.22 uM 24 h 0.22 0.94 0.05 0.35 1.24 1.24
135962 BRD-K92303087 JURKAT 0.74 uM 24 h 0.24 1.01 0.12 0.0 0.0 0.0
136077 BRD-K92303087 THP1 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136108 BRD-K92303087 YAPC 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).