CMap Candidate Details
Structure:
| CMap ID: | C03880 |
| Pert ID: | BRD-K20745393 |
| Compound Name: | olprinone |
| Targets: | PDE3A |
| MoA: | phosphodiesterase inhibitor |
| SMILES: | Cc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 96801 | BRD-K20745393 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121366 | BRD-K20745393 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 121409 | BRD-K20745393 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.25 | -0.84 | 0.18 |
| 121438 | BRD-K20745393 | HT29 | 0.125 uM | 24 h | 0.22 | 0.93 | 0.05 | 0.0 | 0.0 | 0.0 |
| 121513 | BRD-K20745393 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129436 | BRD-K20745393 | HA1E | 2.22 uM | 24 h | 0.14 | 0.59 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129521 | BRD-K20745393 | MCF??7.00 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |