CMap Candidate Details
Structure:
| CMap ID: | C03888 |
| Pert ID: | BRD-K36680103 |
| Compound Name: | omecamtiv-mecarbil |
| Targets: | MYBPC3 |
| MoA: | cardiac myosin activator |
| SMILES: | COC(=O)N1CCN(Cc2cccc(NC(=O)Nc3ccc(C)nc3)c2F)CC1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 120580 | BRD-K36680103 | A549 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.28 | 1.0 | 0.42 |
| 120609 | BRD-K36680103 | HA1E | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120685 | BRD-K36680103 | HT29 | 10 uM | 24 h | 0.23 | 0.97 | 0.08 | -0.3 | -1.0 | 0.54 |
| 120739 | BRD-K36680103 | JURKAT | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.54 |
| 120792 | BRD-K36680103 | PC3 | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120847 | BRD-K36680103 | YAPC | 0.125 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128998 | BRD-K36680103 | A375 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129044 | BRD-K36680103 | HELA | 0.01 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 129072 | BRD-K36680103 | MCF??7.00 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |