CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03897
Pert ID:	BRD-A19736161
Compound Name:	ondansetron
Targets:	HTR1A\|HTR1B\|HTR3A\|HTR3B\|HTR4\|OPRM1
MoA:	serotonin receptor antagonist
SMILES:	Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6623	BRD-A19736161	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7059	BRD-A19736161	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7381	BRD-A19736161	HA1E	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
7514	BRD-A19736161	HCC515	10 uM	6 h	-0.25	-1.05	0.24	0.0	0.0	0.0
20186	BRD-A19736161	HEPG2	10 uM	6 h	0.0	0.0	0.0	-0.25	-0.85	0.19
20830	BRD-A19736161	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.88	0.25
21675	BRD-A19736161	VCAP	10 uM	6 h	0.26	1.1	0.24	0.0	0.0	0.0
91338	BRD-A19736161	HUH7	12 uM	72 h	0.25	1.06	0.19	0.32	1.15	0.89
120934	BRD-A19736161	HEK293	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120983	BRD-A19736161	HELA	1.11 uM	24 h	0.17	0.69	0.0	0.0	0.0	0.0
121092	BRD-A19736161	YAPC	3.33 uM	24 h	0.0	0.0	0.0	0.33	1.18	0.98
129182	BRD-A19736161	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
129214	BRD-A19736161	PC3	0.74 uM	24 h	0.17	0.7	0.0	0.0	0.0	0.0

Summary