CMap Candidate Details
Structure:
| CMap ID: | C03916 |
| Pert ID: | BRD-K41434598 |
| Compound Name: | org-9768 |
| Targets: | ADRA2A |
| MoA: | adrenergic receptor antagonist |
| SMILES: | CC1(CN)Cc2ccccc2C1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 123238 | BRD-K41434598 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.21 | -0.71 | 0.03 |
| 123290 | BRD-K41434598 | HEK293 | 0.125 uM | 24 h | 0.19 | 0.8 | 0.0 | -0.21 | -0.7 | 0.03 |
| 123422 | BRD-K41434598 | PC3 | 3.33 uM | 24 h | 0.26 | 1.09 | 0.23 | 0.0 | 0.0 | 0.0 |
| 123460 | BRD-K41434598 | THP1 | 3.33 uM | 24 h | -0.17 | -0.72 | 0.0 | -0.27 | -0.9 | 0.28 |
| 123495 | BRD-K41434598 | YAPC | 0.37 uM | 24 h | -0.28 | -1.18 | 0.51 | 0.0 | 0.0 | 0.0 |
| 131554 | BRD-K41434598 | A549 | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131589 | BRD-K41434598 | HA1E | 0.74 uM | 24 h | -0.25 | -1.03 | 0.2 | -0.39 | -1.3 | 1.6 |
| 131662 | BRD-K41434598 | HELA | 0.08 uM | 24 h | -0.27 | -1.12 | 0.39 | 0.0 | 0.0 | 0.0 |
| 131688 | BRD-K41434598 | HT29 | 0.74 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.87 | 0.22 |
| 131727 | BRD-K41434598 | HUVEC | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.32 | -1.08 | 0.81 |
| 131781 | BRD-K41434598 | JURKAT | 0.08 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131825 | BRD-K41434598 | MCF10A | 0.01 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 131860 | BRD-K41434598 | MCF??7.00 | 0.01 uM | 24 h | -0.26 | -1.07 | 0.27 | 0.0 | 0.0 | 0.0 |
| 131894 | BRD-K41434598 | MDAMB231 | 0.25 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |