CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03938
Pert ID:	BRD-K80082640
Compound Name:	otamixaban
Targets:	F10
MoA:	coagulation factor inhibitor
SMILES:	COC(=O)[C@H](Cc1cccc(c1)C(N)=N)[C@@H](C)NC(=O)c1ccc(cc1)-c1cc[n+]([O-])cc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
125576	BRD-K80082640	A375	0.04 uM	24 h	0.0	0.0	0.0	0.37	1.31	1.59
125672	BRD-K80082640	HELA	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
125725	BRD-K80082640	HUVEC	0.37 uM	24 h	0.0	0.0	0.0	0.34	1.2	1.1
125772	BRD-K80082640	JURKAT	0.37 uM	24 h	0.0	0.0	0.0	-0.26	-0.87	0.23
125799	BRD-K80082640	MCF10A	3.33 uM	24 h	0.0	0.0	0.0	0.26	0.92	0.25
125871	BRD-K80082640	PC3	0.37 uM	24 h	-0.21	-0.88	0.03	0.27	0.95	0.31
125924	BRD-K80082640	YAPC	0.04 uM	24 h	0.0	0.0	0.0	-0.33	-1.1	0.86
133661	BRD-K80082640	A549	0.03 uM	24 h	-0.26	-1.09	0.33	0.2	0.71	0.02
133694	BRD-K80082640	HA1E	0.01 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
133728	BRD-K80082640	HEK293	0.01 uM	24 h	0.2	0.83	0.0	0.27	0.96	0.33
133793	BRD-K80082640	HT29	0.25 uM	24 h	0.0	0.0	0.0	-0.38	-1.28	1.45
133879	BRD-K80082640	MCF??7.00	2.22 uM	24 h	0.26	1.08	0.21	-0.32	-1.09	0.84
133908	BRD-K80082640	MDAMB231	0.01 uM	24 h	0.0	0.0	0.0	-0.25	-0.83	0.15
133973	BRD-K80082640	THP1	0.74 uM	24 h	0.0	0.0	0.0	-0.28	-0.94	0.36

Summary