Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03950
Pert ID: BRD-K92467929
Compound Name: oxandrolone
Targets: AR
MoA: androgen receptor agonist
SMILES: C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)OC[C@]4(C)[C@H]3CC[C@]12C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128368 BRD-K92467929 A549 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
128416 BRD-K92467929 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
128526 BRD-K92467929 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128582 BRD-K92467929 MCF10A 0.125 uM 24 h 0.0 0.0 0.0 -0.43 -1.44 15.35
128619 BRD-K92467929 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128699 BRD-K92467929 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
136161 BRD-K92467929 A375 0.08 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
136207 BRD-K92467929 HA1E 2.22 uM 24 h 0.23 0.98 0.09 0.26 0.92 0.24
136249 BRD-K92467929 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136282 BRD-K92467929 HT29 2.22 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
136327 BRD-K92467929 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
136356 BRD-K92467929 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136378 BRD-K92467929 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).