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CMap Candidate Details

Structure:
CMap ID: C03952
Pert ID: BRD-K25394294
Compound Name: oxaprozin
Targets: PTGS1|PTGS2
MoA: cyclooxygenase inhibitor
SMILES: OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5599 BRD-K25394294 HCC515 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
6175 BRD-K25394294 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24423 BRD-K25394294 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25344 BRD-K25394294 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37621 BRD-K25394294 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37883 BRD-K25394294 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38449 BRD-K25394294 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
38699 BRD-K25394294 PHH 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.06
52141 BRD-K25394294 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
53503 BRD-K25394294 HUH7 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119968 BRD-K25394294 A549 1.11 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
120015 BRD-K25394294 HA1E 10 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
120040 BRD-K25394294 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
120083 BRD-K25394294 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128856 BRD-K25394294 YAPC 0.01 uM 24 h -0.23 -0.96 0.09 0.27 0.95 0.32
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).