CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03953
Pert ID:	BRD-K02079473
Compound Name:	oxatomide
Targets:	HRH1
MoA:	histamine receptor antagonist
SMILES:	O=c1[nH]c2ccccc2n1CCCN1CCN(CC1)C(c1ccccc1)c1ccccc1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
91143	BRD-K02079473	HUH7	8 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0
122862	BRD-K02079473	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
122901	BRD-K02079473	HEK293	10 uM	24 h	0.0	0.0	0.0	-0.3	-1.0	0.55
122942	BRD-K02079473	HELA	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
122977	BRD-K02079473	HT29	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123026	BRD-K02079473	JURKAT	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123116	BRD-K02079473	MDAMB231	10 uM	24 h	0.24	0.99	0.1	0.29	1.02	0.48
123149	BRD-K02079473	PC3	1.11 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
123187	BRD-K02079473	THP1	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131213	BRD-K02079473	A375	2.22 uM	24 h	0.0	0.0	0.0	0.27	0.94	0.3
131249	BRD-K02079473	A549	0.03 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131363	BRD-K02079473	HUVEC	0.08 uM	24 h	0.0	0.0	0.0	-0.24	-0.8	0.12
131403	BRD-K02079473	MCF10A	0.08 uM	24 h	0.0	0.0	0.0	0.28	0.99	0.42
131441	BRD-K02079473	MCF??7.00	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
131500	BRD-K02079473	YAPC	2.22 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary