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CMap Candidate Details

Structure:
CMap ID: C03974
Pert ID: BRD-K59037100
Compound Name: oxybenzone
Targets: LIPE
MoA: lipase inhibitor
SMILES: COc1ccc(C(=O)c2ccccc2)c(O)c1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3381 BRD-K59037100 HCC515 10 uM 6 h -0.24 -0.98 0.12 0.0 0.0 0.0
3974 BRD-K59037100 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
44993 BRD-K59037100 ASC 10 uM 24 h 0.26 1.08 0.21 -0.31 -1.04 0.67
45285 BRD-K59037100 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46109 BRD-K59037100 NPC 10 uM 24 h -0.22 -0.93 0.07 -0.19 -0.63 0.0
46422 BRD-K59037100 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
46748 BRD-K59037100 SKB 10 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
123805 BRD-K59037100 A375 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
123845 BRD-K59037100 A549 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
123874 BRD-K59037100 HA1E 1.11 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
123911 BRD-K59037100 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
123950 BRD-K59037100 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124012 BRD-K59037100 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124065 BRD-K59037100 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.93
124194 BRD-K59037100 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124246 BRD-K59037100 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132235 BRD-K59037100 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.15
132259 BRD-K59037100 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132277 BRD-K59037100 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
132303 BRD-K59037100 PC3 0.01 uM 24 h 0.21 0.88 0.01 -0.18 -0.6 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).