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CMap Candidate Details

Structure:
CMap ID: C03975
Pert ID: BRD-K04185004
Compound Name: oxybuprocaine
Targets: SCN10A
MoA: local anesthetic
SMILES: CCCCOc1cc(ccc1N)C(=O)OCCN(CC)CC
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1868 BRD-K04185004 HCC515 10 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
2589 BRD-K04185004 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.44
42263 BRD-K04185004 ASC 10 uM 24 h -0.29 -1.22 0.62 0.3 1.08 0.65
42599 BRD-K04185004 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43458 BRD-K04185004 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43765 BRD-K04185004 PHH 10 uM 24 h 0.31 1.28 0.64 0.28 1.0 0.42
44046 BRD-K04185004 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
122557 BRD-K04185004 A375 0.37 uM 24 h 0.26 1.07 0.19 -0.42 -1.41 2.02
122585 BRD-K04185004 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122609 BRD-K04185004 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122644 BRD-K04185004 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
122663 BRD-K04185004 HELA 10 uM 24 h 0.0 0.0 0.0 0.2 0.69 0.01
122737 BRD-K04185004 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122777 BRD-K04185004 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.01
122823 BRD-K04185004 YAPC 0.04 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.21
131006 BRD-K04185004 HT29 0.01 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
131059 BRD-K04185004 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
131094 BRD-K04185004 MCF??7.00 0.01 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
131158 BRD-K04185004 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).