CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C03980
Pert ID:	BRD-K16195444
Compound Name:	oxymetazoline
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|HTR1B\|HTR1D\|HTR2C
MoA:	adrenergic receptor agonist
SMILES:	Cc1cc(c(O)c(C)c1CC1=NCCN1)C(C)(C)C
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2841	BRD-K16195444	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3336	BRD-K16195444	HCC515	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
3730	BRD-K16195444	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.26	-0.89	0.27
44877	BRD-K16195444	ASC	10 uM	24 h	0.0	0.0	0.0	-0.31	-1.06	0.73
45180	BRD-K16195444	HEPG2	10 uM	6 h	-0.25	-1.06	0.26	-0.29	-0.98	0.48
45994	BRD-K16195444	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46312	BRD-K16195444	PHH	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
46627	BRD-K16195444	SKB	10 uM	24 h	0.0	0.0	0.0	-0.25	-0.83	0.16
91007	BRD-K16195444	HUH7	12.5 uM	72 h	0.0	0.0	0.0	-0.29	-0.98	0.48
100144	BRD-K16195444	U2OS	10 uM	6 h	0.0	0.0	0.0	0.27	0.95	0.31
120234	BRD-K16195444	A375	0.125 uM	24 h	-0.19	-0.78	0.0	0.0	0.0	0.0
120269	BRD-K16195444	A549	0.125 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120358	BRD-K16195444	HELA	10 uM	3 h	0.27	1.12	0.26	-0.26	-0.89	0.27
120398	BRD-K16195444	MCF??7.00	3.33 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
120463	BRD-K16195444	YAPC	10 uM	24 h	-0.19	-0.78	0.0	0.25	0.87	0.17
128940	BRD-K16195444	HT29	0.74 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
128972	BRD-K16195444	PC3	2.22 uM	24 h	0.0	0.0	0.0	-0.34	-1.13	1.01

Summary