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CMap Candidate Details

Structure:
CMap ID: C03985
Pert ID: BRD-K31841515
Compound Name: oxypurinol
Targets: XDH
MoA: xanthine oxidase inhibitor
SMILES: O=c1[nH]c2n[nH]cc2c(=O)[nH]1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90596 BRD-K31841515 HCT116 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90689 BRD-K31841515 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97989 BRD-K31841515 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.18
98065 BRD-K31841515 P1A82 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
120515 BRD-K31841515 A375 0.37 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
120550 BRD-K31841515 A549 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.34
120632 BRD-K31841515 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120651 BRD-K31841515 HT29 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
120701 BRD-K31841515 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120750 BRD-K31841515 MCF??7.00 10 uM 24 h 0.28 1.18 0.39 0.0 0.0 0.0
120773 BRD-K31841515 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120807 BRD-K31841515 YAPC 0.125 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).