Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C03996
Pert ID: BRD-K96671969
Compound Name: PA-824
Targets: FASN
MoA: nitric oxide donor
SMILES: [O-][N+](=O)c1cn2C[C@@H](COc2n1)OCc1ccc(OC(F)(F)F)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
128395 BRD-K96671969 A549 0.125 uM 24 h -0.22 -0.93 0.07 0.0 0.0 0.0
128453 BRD-K96671969 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
128511 BRD-K96671969 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128563 BRD-K96671969 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128611 BRD-K96671969 MCF??7.00 0.37 uM 24 h -0.3 -1.25 0.71 0.23 0.82 0.1
128655 BRD-K96671969 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128688 BRD-K96671969 PC3 10 uM 24 h 0.22 0.91 0.03 0.36 1.26 1.29
128735 BRD-K96671969 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136192 BRD-K96671969 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136237 BRD-K96671969 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136272 BRD-K96671969 HELA 2.22 uM 24 h 0.26 1.09 0.22 0.22 0.78 0.07
136317 BRD-K96671969 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136389 BRD-K96671969 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).