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CMap Candidate Details

Structure:
CMap ID: C00040
Pert ID: BRD-K91623615
Compound Name: ABT-751
Targets: TUBB
MoA: tubulin polymerization inhibitor
SMILES: COc1ccc(cc1)S(=O)(=O)Nc1cccnc1Nc1ccc(O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1174 BRD-K91623615 PC3 10 uM 24 h -0.24 -1.0 0.15 -0.3 -1.0 0.52
1234 BRD-K91623615 A549 1.11 uM 24 h -0.28 -1.16 0.45 0.0 0.0 0.0
1309 BRD-K91623615 MCF??7.00 10 uM 6 h 0.26 1.1 0.24 0.0 0.0 0.0
1365 BRD-K91623615 U2OS 10 uM 48 h 0.0 0.0 0.0 -0.29 -0.99 0.5
9047 BRD-K91623615 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9543 BRD-K91623615 AGS 10 uM 6 h -0.26 -1.09 0.31 -0.24 -0.8 0.12
9850 BRD-K91623615 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9955 BRD-K91623615 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10206 BRD-K91623615 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10876 BRD-K91623615 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
11039 BRD-K91623615 HT29 10 uM 24 h -0.18 -0.74 0.0 0.21 0.75 0.04
11610 BRD-K91623615 NCIH2073 10 uM 6 h -0.27 -1.11 0.37 0.0 0.0 0.0
11868 BRD-K91623615 NCIH508 10 uM 6 h -0.23 -0.96 0.09 -0.42 -1.41 2.02
12166 BRD-K91623615 NCIH596 10 uM 6 h -0.23 -0.94 0.08 -0.34 -1.13 0.98
12404 BRD-K91623615 NOMO1 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.81 0.14
12899 BRD-K91623615 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13054 BRD-K91623615 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13394 BRD-K91623615 U937 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.91
13513 BRD-K91623615 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90835 BRD-K91623615 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).