Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C04025
Pert ID: BRD-K41524689
Compound Name: paracetamol
Targets: FAAH|PTGS1|PTGS2|TRPV1
MoA: cyclooxygenase inhibitor
SMILES: CC(=O)Nc1ccc(O)cc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
52672 BRD-K41524689 A549 0.25 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.08
52714 BRD-K41524689 HEPG2 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90772 BRD-K41524689 HPTEC 1000 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
90869 BRD-K41524689 MCF10A 1.67 uM 3 h -0.26 -1.08 0.31 0.29 1.03 0.52
99518 BRD-K41524689 U2OS 12.5 uM 6 h 0.2 0.83 0.0 0.0 0.0 0.0
123345 BRD-K41524689 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123425 BRD-K41524689 PC3 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.38
123463 BRD-K41524689 THP1 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
123497 BRD-K41524689 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131530 BRD-K41524689 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131592 BRD-K41524689 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131633 BRD-K41524689 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
131664 BRD-K41524689 HELA 0.03 uM 24 h -0.23 -0.97 0.11 -0.3 -1.0 0.52
131731 BRD-K41524689 HUVEC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131785 BRD-K41524689 JURKAT 0.01 uM 24 h 0.24 1.02 0.13 0.0 0.0 0.0
131862 BRD-K41524689 MCF??7.00 2.22 uM 24 h -0.32 -1.34 0.98 -0.23 -0.78 0.09
131897 BRD-K41524689 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).