CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04029
Pert ID:	BRD-K02407574
Compound Name:	parbendazole
Targets:	TUBB
MoA:	tubulin polymerization inhibitor
SMILES:	CCCCc1ccc2[nH]c(NC(=O)OC)nc2c1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
1216	BRD-K02407574	PC3	10 uM	24 h	-0.27	-1.13	0.4	0.0	0.0	0.0
9334	BRD-K02407574	AGS	0.3 uM	6 h	0.0	0.0	0.0	0.21	0.76	0.05
9640	BRD-K02407574	H1299	0.3 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
10438	BRD-K02407574	HCT116	0.3 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
11390	BRD-K02407574	NCIH2073	0.3 uM	6 h	-0.2	-0.82	0.0	0.0	0.0	0.0
11962	BRD-K02407574	NCIH596	0.3 uM	6 h	0.0	0.0	0.0	-0.24	-0.82	0.15
12245	BRD-K02407574	NOMO1	0.3 uM	6 h	-0.21	-0.86	0.02	0.0	0.0	0.0
12993	BRD-K02407574	THP1	0.3 uM	6 h	0.29	1.22	0.47	0.0	0.0	0.0
13187	BRD-K02407574	U937	0.3 uM	6 h	0.0	0.0	0.0	-0.31	-1.04	0.65
13439	BRD-K02407574	VCAP	0.3 uM	24 h	0.0	0.0	0.0	0.26	0.93	0.26
52061	BRD-K02407574	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
96290	BRD-K02407574	U2OS	10 uM	24 h	0.0	0.0	0.0	-0.35	-1.16	1.11
97689	BRD-K02407574	NKDBA	10 uM	24 h	0.27	1.13	0.3	0.41	1.47	2.24
117348	BRD-K02407574	A375	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117386	BRD-K02407574	A549	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117426	BRD-K02407574	HA1E	10 uM	24 h	0.0	0.0	0.0	0.3	1.05	0.58
117471	BRD-K02407574	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
117519	BRD-K02407574	HEPG2	10 uM	24 h	-0.21	-0.89	0.04	-0.29	-0.97	0.45
117562	BRD-K02407574	HT29	0.37 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary