Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C04039
Pert ID: BRD-K98548675
Compound Name: parthenolide
Targets:
MoA: NFkB pathway inhibitor
SMILES: C\C1=C/CC[C@@]2(C)O[C@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3083 BRD-K98548675 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3307 BRD-K98548675 HCC515 10 uM 24 h -0.25 -1.04 0.22 0.3 1.05 0.58
3659 BRD-K98548675 PC3 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.39
3998 BRD-K98548675 VCAP 10 uM 6 h 0.22 0.92 0.04 -0.4 -1.33 1.76
9557 BRD-K98548675 AGS 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.13
10640 BRD-K98548675 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10887 BRD-K98548675 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.69 0.02
11189 BRD-K98548675 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
11627 BRD-K98548675 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11883 BRD-K98548675 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12181 BRD-K98548675 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.81
12419 BRD-K98548675 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12914 BRD-K98548675 SW480 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.29
13406 BRD-K98548675 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44467 BRD-K98548675 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44632 BRD-K98548675 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45061 BRD-K98548675 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45602 BRD-K98548675 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46170 BRD-K98548675 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46485 BRD-K98548675 PHH 10 uM 24 h 0.25 1.03 0.14 -0.37 -1.25 1.35
46815 BRD-K98548675 SKB 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
87309 BRD-K98548675 BJAB 10 uM 3 h 0.21 0.86 0.01 0.0 0.0 0.0
87373 BRD-K98548675 HBL1 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.34
87423 BRD-K98548675 K562 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
87470 BRD-K98548675 KMS34 2.5 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
87530 BRD-K98548675 MINO 2.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
87575 BRD-K98548675 NALM6 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87625 BRD-K98548675 OCILY10 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87675 BRD-K98548675 OCILY19 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87726 BRD-K98548675 OCILY3 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
87774 BRD-K98548675 SKMEL5 10 uM 24 h -0.17 -0.69 0.0 -0.38 -1.29 1.53
87794 BRD-K98548675 THP1 2.5 uM 24 h -0.22 -0.92 0.06 0.32 1.15 0.88
87838 BRD-K98548675 TMD8 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97612 BRD-K98548675 NKDBA 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).