CMap Candidate Details
Structure:
| CMap ID: | C04049 |
| Pert ID: | BRD-K88742110 |
| Compound Name: | PCI-34051 |
| Targets: | HDAC1|HDAC10|HDAC6|HDAC8 |
| MoA: | HDAC inhibitor |
| SMILES: | COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 47381 | BRD-K88742110 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 48909 | BRD-K88742110 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 49730 | BRD-K88742110 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 90522 | BRD-K88742110 | PC3 | 0.66 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 98778 | BRD-K88742110 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.31 | -1.04 | 0.68 |
| 99104 | BRD-K88742110 | NEU | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119191 | BRD-K88742110 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119247 | BRD-K88742110 | HA1E | 1.11 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119279 | BRD-K88742110 | HCC515 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.22 | 1.15 |
| 119306 | BRD-K88742110 | HEPG2 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119333 | BRD-K88742110 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.0 | 0.55 |