CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04059
Pert ID:	BRD-K12079898
Compound Name:	PD-160170
Targets:	NPY1R
MoA:	neuropeptide receptor antagonist
SMILES:	CC(C)c1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+]([O-])=O
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
2837	BRD-K12079898	HA1E	10 uM	24 h	0.25	1.04	0.14	0.0	0.0	0.0
3142	BRD-K12079898	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
3467	BRD-K12079898	PC3	10 uM	24 h	0.2	0.84	0.0	0.3	1.05	0.58
3725	BRD-K12079898	VCAP	10 uM	24 h	0.23	0.94	0.06	0.0	0.0	0.0
39092	BRD-K12079898	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39427	BRD-K12079898	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
39630	BRD-K12079898	ASC	10 uM	24 h	0.25	1.04	0.14	0.0	0.0	0.0
39947	BRD-K12079898	HEPG2	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
40228	BRD-K12079898	HT29	10 uM	6 h	0.0	0.0	0.0	-0.4	-1.35	2.01
40452	BRD-K12079898	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
40753	BRD-K12079898	NEU	10 uM	24 h	-0.32	-1.32	0.84	-0.27	-0.91	0.29
41053	BRD-K12079898	NPC	10 uM	24 h	0.22	0.91	0.04	-0.36	-1.22	1.24
41382	BRD-K12079898	SKB	10 uM	24 h	-0.19	-0.79	0.0	0.27	0.94	0.29

Summary