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CMap Candidate Details

Structure:
CMap ID: C04063
Pert ID: BRD-K47761761
Compound Name: PD-168077
Targets: DRD2
MoA: dopamine receptor agonist
SMILES: Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25833 BRD-K47761761 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25943 BRD-K47761761 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26372 BRD-K47761761 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26703 BRD-K47761761 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27006 BRD-K47761761 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
27315 BRD-K47761761 HT29 10 uM 6 h 0.27 1.14 0.32 0.26 0.93 0.28
27560 BRD-K47761761 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
27946 BRD-K47761761 NEU 10 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
28260 BRD-K47761761 NPC 10 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
28650 BRD-K47761761 PC3 10 uM 6 h 0.0 0.0 0.0 0.39 1.4 2.18
28892 BRD-K47761761 PHH 10 uM 24 h -0.22 -0.91 0.05 0.31 1.09 0.67
29223 BRD-K47761761 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29642 BRD-K47761761 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).