CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C00407
Pert ID:	BRD-K93188295
Compound Name:	ARC-239
Targets:	ADRA2A\|ADRA2B\|ADRA2C
MoA:	adrenergic receptor antagonist
SMILES:	COc1ccccc1N1CCN(CCN2C(=O)c3ccccc3C(C)(C)C2=O)CC1
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
6815	BRD-K93188295	A375	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7040	BRD-K93188295	A549	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
7496	BRD-K93188295	HA1E	10 uM	6 h	0.24	1.0	0.11	0.0	0.0	0.0
7730	BRD-K93188295	HCC515	10 uM	6 h	0.28	1.15	0.32	-0.25	-0.84	0.18
7926	BRD-K93188295	HT29	10 uM	24 h	-0.23	-0.96	0.09	-0.3	-1.0	0.55
8119	BRD-K93188295	MCF??7.00	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8415	BRD-K93188295	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
8736	BRD-K93188295	VCAP	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary