Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00409
Pert ID: BRD-K72726508
Compound Name: arcyriaflavin-a
Targets: CCND1|CDK4
MoA: CDK inhibitor
SMILES: O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5361 BRD-K72726508 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5682 BRD-K72726508 HCC515 10 uM 24 h 0.22 0.91 0.03 -0.25 -0.85 0.19
6053 BRD-K72726508 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.65
6216 BRD-K72726508 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6587 BRD-K72726508 VCAP 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
37186 BRD-K72726508 A375 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.18 1.14
37307 BRD-K72726508 A549 10 uM 24 h -0.26 -1.09 0.31 0.0 0.0 0.0
37730 BRD-K72726508 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37941 BRD-K72726508 HEPG2 10 uM 6 h -0.17 -0.72 0.0 -0.32 -1.07 0.75
38221 BRD-K72726508 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38547 BRD-K72726508 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38772 BRD-K72726508 PHH 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
38999 BRD-K72726508 SKB 10 uM 24 h 0.0 0.0 0.0 0.18 0.65 0.01
99434 BRD-K72726508 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).