CKDkb: a knowledge base and platform for drug development against non-alcoholic fatty liver disease

Structure:

CMap ID:	C04107
Pert ID:	BRD-K60770992
Compound Name:	pergolide
Targets:	ADRA1A\|ADRA1B\|ADRA1D\|ADRA2A\|ADRA2B\|ADRA2C\|DRD1\|DRD2\|DRD3\|DRD4\|DRD5\|HTR1A\|HTR1B\|HTR1D\|HTR2A\|HTR2B\|HTR2C
MoA:	dopamine receptor agonist
SMILES:	CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc1c[nH]c3cccc2c13
InchiKey:
Compound Aliases:

The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).
Score ID	Pert ID	Cell Line	Pert Dose	Pert Time	Raw Score (GSE126848)	Normalized Score (GSE126848)	fdr_q_nlog10 (GSE126848)	Raw Score (GSE135251)	Normalized Score (GSE135251)	fdr_q_nlog10 (GSE135251)
5348	BRD-K60770992	HA1E	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5658	BRD-K60770992	HCC515	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
5936	BRD-K60770992	HEPG2	10 uM	6 h	-0.31	-1.27	0.74	-0.21	-0.7	0.03
6206	BRD-K60770992	PC3	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
24463	BRD-K60770992	A375	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
24931	BRD-K60770992	HT29	10 uM	6 h	-0.23	-0.95	0.09	0.0	0.0	0.0
25400	BRD-K60770992	VCAP	10 uM	24 h	0.0	0.0	0.0	-0.36	-1.21	1.24
37406	BRD-K60770992	A549	10 uM	6 h	0.0	0.0	0.0	0.0	0.0	0.0
37707	BRD-K60770992	ASC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38528	BRD-K60770992	NPC	10 uM	24 h	0.0	0.0	0.0	0.0	0.0	0.0
38756	BRD-K60770992	PHH	10 uM	24 h	0.0	0.0	0.0	-0.34	-1.14	1.02
51345	BRD-K60770992	MCF??7.00	10 uM	6 h	0.27	1.14	0.31	-0.35	-1.18	1.14
90952	BRD-K60770992	HUH7	10 uM	72 h	0.0	0.0	0.0	0.0	0.0	0.0

Summary