Logo 1 Logo 2

CMap Candidate Details

Structure:
CMap ID: C00411
Pert ID: BRD-K63792901
Compound Name: arecaidine-but-2-ynyl-ester
Targets: CHRM2
MoA: acetylcholine receptor agonist
SMILES: CC#CCOC(=O)C1=CCCN(C)C1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4131 BRD-K63792901 HA1E 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
4459 BRD-K63792901 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4703 BRD-K63792901 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
4948 BRD-K63792901 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39158 BRD-K63792901 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39337 BRD-K63792901 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39734 BRD-K63792901 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40030 BRD-K63792901 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40302 BRD-K63792901 HT29 10 uM 6 h 0.26 1.09 0.23 0.0 0.0 0.0
40628 BRD-K63792901 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.41 1.44 2.21
41152 BRD-K63792901 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
41490 BRD-K63792901 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99324 BRD-K63792901 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).