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CMap Candidate Details

Structure:
CMap ID: C04115
Pert ID: BRD-K10995081
Compound Name: perphenazine
Targets: CALM1|DRD1|DRD2|HRH1|HTR2A|HTR2C|HTR6|HTR7
MoA: dopamine receptor antagonist
SMILES: OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5183 BRD-K10995081 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5578 BRD-K10995081 HCC515 10 uM 24 h -0.21 -0.87 0.02 0.0 0.0 0.0
6366 BRD-K10995081 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37267 BRD-K10995081 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37593 BRD-K10995081 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37872 BRD-K10995081 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.34 1.22 1.15
38055 BRD-K10995081 HT29 10 uM 6 h 0.18 0.73 0.0 0.32 1.12 0.76
38183 BRD-K10995081 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38428 BRD-K10995081 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38912 BRD-K10995081 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
50153 BRD-K10995081 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51432 BRD-K10995081 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100074 BRD-K10995081 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).