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CMap Candidate Details

Structure:
CMap ID: C00412
Pert ID: BRD-K23922020
Compound Name: arecaidine-propargyl-ester
Targets: CHRM1|CHRM2|CHRM3|CHRM4
MoA: acetylcholine receptor agonist
SMILES: CN1CCC=C(C1)C(=O)OCC#C
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1747 BRD-K23922020 HA1E 10 uM 6 h -0.19 -0.8 0.0 -0.3 -1.03 0.62
1903 BRD-K23922020 HCC515 10 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
2384 BRD-K23922020 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2631 BRD-K23922020 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
41746 BRD-K23922020 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41920 BRD-K23922020 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42330 BRD-K23922020 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
42657 BRD-K23922020 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42960 BRD-K23922020 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43172 BRD-K23922020 MCF??7.00 10 uM 24 h -0.26 -1.09 0.33 -0.25 -0.83 0.17
43521 BRD-K23922020 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43819 BRD-K23922020 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).