CMap Candidate Details
Structure:
| CMap ID: | C04138 |
| Pert ID: | BRD-K07955840 |
| Compound Name: | PF-05212384 |
| Targets: | MTOR|PIK3CA |
| MoA: | mTOR inhibitor; PI3K inhibitor |
| SMILES: | CN(C)C1CCN(CC1)C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2CCOCC2)N2CCOCC2)cc1 |
| InchiKey: | |
| Compound Aliases: |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 515 | BRD-K07955840 | BJAB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 563 | BRD-K07955840 | HBL1 | 2.5 uM | 4 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 608 | BRD-K07955840 | K562 | 2.5 uM | 4 h | -0.21 | -0.88 | 0.03 | -0.34 | -1.16 | 1.11 |
| 653 | BRD-K07955840 | KMS34 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 699 | BRD-K07955840 | MINO | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.19 | -0.65 | 0.01 |
| 747 | BRD-K07955840 | NALM6 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 775 | BRD-K07955840 | OCILY19 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 820 | BRD-K07955840 | OCILY3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.05 |
| 889 | BRD-K07955840 | SKMEL5 | 2.5 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.3 | -1.02 | 0.62 |
| 930 | BRD-K07955840 | THP1 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.22 | -0.74 | 0.05 |
| 976 | BRD-K07955840 | TMD8 | 10 uM | 4 h | 0.24 | 1.01 | 0.12 | 0.0 | 0.0 | 0.0 |