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CMap Candidate Details

Structure:
CMap ID: C04142
Pert ID: BRD-K68997413
Compound Name: PF-3845
Targets: FAAH
MoA: FAAH inhibitor
SMILES: FC(F)(F)c1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)nc1
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9223 BRD-K68997413 A549 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.21
9486 BRD-K68997413 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9791 BRD-K68997413 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9936 BRD-K68997413 HA1E 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
10185 BRD-K68997413 HCC515 10 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.2
10572 BRD-K68997413 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10830 BRD-K68997413 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11004 BRD-K68997413 HT29 10 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
11191 BRD-K68997413 MCF??7.00 10 uM 24 h -0.16 -0.66 0.0 0.0 0.0 0.0
11552 BRD-K68997413 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12368 BRD-K68997413 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.34
13030 BRD-K68997413 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13337 BRD-K68997413 U937 10 uM 6 h -0.29 -1.22 0.6 0.0 0.0 0.0
13665 BRD-K68997413 VCAP 10 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
96713 BRD-K68997413 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96761 BRD-K68997413 PC3 10 uM 24 h -0.2 -0.83 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).