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CMap Candidate Details

Structure:
CMap ID: C04144
Pert ID: BRD-K93788137
Compound Name: PF-431396
Targets: PTK2|PTK2B
MoA: focal adhesion kinase inhibitor
SMILES: CN(c1ccccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
InchiKey:
Compound Aliases:

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91986 BRD-K93788137 A375 0.04 uM 24 h -0.26 -1.09 0.33 0.23 0.81 0.09
92012 BRD-K93788137 BT20 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92060 BRD-K93788137 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92090 BRD-K93788137 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92129 BRD-K93788137 HS578T 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92182 BRD-K93788137 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92229 BRD-K93788137 MCF10A 10 uM 3 h 0.0 0.0 0.0 0.46 1.62 2.41
92249 BRD-K93788137 MCF??7.00 3.33 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
92285 BRD-K93788137 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.41 1.47 2.24
92331 BRD-K93788137 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
92360 BRD-K93788137 SKBR3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).